IMPURITY RADIONUCLIDES AT A RADIOPHARMACEUTICAL PRODUCTION BASED ON A 18F

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Published: Mar 30, 2017
Keywords:
радиофармпрепараты, радионуклиды, 18F-фтордезоксиглюкоза, 18F-холин radiopharmaceuticals, radionuclide, 18F-fluorodeoxyglucose, 18F-choline

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S. DOBROVOLSKI
Белорусский государственный университет, Минск
A. SAVKOV
Belarusian State University, Minsk
D. BRINKEVICH
Belarusian State University, Minsk
S. BRINKEVICH
Belarusian State University, Minsk
https://orcid.org/0000-0003-1661-5272
N. VABISHCHEVICH
Polotsk State University

Abstract

The distribution of radionuclides in various cartridges during 18F-fluorodeoxyglucose and 18F-choline manufacture using IBA Cyclone 18/9 cyclotron was investigated in order to develop evidence-based concept of long-term storage of radioactive waste of radiopharmaceuticals for positron emission tomography. Isotopic composition of long-lived (t1/2 = 10–312 days) radionuclides was detected. It was shown that the shelf life of QMA cartridges should be at least six months. Various mechanisms of radionuclides of metals entering in cartridges at the synthesis of radiopharmaceuticals based on 18F was discussed.

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How to Cite
DOBROVOLSKI, S., SAVKOV, A., BRINKEVICH, D., BRINKEVICH, S., & VABISHCHEVICH, N. (2017). IMPURITY RADIONUCLIDES AT A RADIOPHARMACEUTICAL PRODUCTION BASED ON A 18F. Vestnik of Polotsk State University. Part C. Fundamental Sciences, (4), 64-71. Retrieved from https://journals.psu.by/fundamental/article/view/3488
Issue
No. 4 (2017)
Section
Physics
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

D. BRINKEVICH, Belarusian State University, Minsk

канд. физ.-мат. наук

S. BRINKEVICH, Belarusian State University, Minsk

канд. хим. наук, доц.

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